Vitamin B12, an essential nutrient also known as cobalamin is necessary for the human body. This water-soluble vitamin plays an important role, supporting the formation of red blood cells, DNA synthesis and neurological functioning.
A lack of cobalamin can cause pernicious anaemia, an auto-immune condition which affects the cells of the stomach lining, which in turn hampers and reduces the absorption of Vitamin B12, leading to enlargening of cells and an increase in unhealthy red blood cells and levels of homocysteine, which may impact the arteries.
The healthy red blood cells – which carry oxygen to all parts of the body – don’t develop normally with vitamin B12 deficiency, causing the bone marrow to lower the production of red blood cells or reduce the life cycle of RBCs.
“Various factors can cause a deficiency of vitamin B12 in the body. A decrease in intrinsic factor (a kind of protein) can hamper vitamin B12 absorption as can gastritis, stomach and intestinal surgeries, intestinal malabsorption like Crohn’s disease, celiac disease, and stomach infections. Prolonged use of medications or excessive alcohol intake also damages the stomach lining, which may hamper the absorption of vitamin B12. A diet lacking in vitamin B12 may also lead to its deficiency,” Aman Puri, Founder, Steadfast Nutrition, a leading sports and wellness nutrition brand, told Financial Express.com.
Individuals who take a strictly vegetarian diet are often deficient in vitamin B12. Initial symptoms of vitamin B12 deficiency, such as fatigue, nausea, and loss of appetite, are often basic and remain unnoticed, which leads to the deficiency remaining undetected.
“A prolonged deficiency can worsen symtoms, which include shortness of breath, bleeding gums, nerve damage, numbness, tingling of hands, confusion, irritable and depressed behaviour, and decline in cognitive health. Since the body is unable to make healthy red blood cells and transport oxygen to the body, the deficiency leads to weakness and fatigue,” Puri said.
Adults require about 2.2 mcg of vitamin B12 daily, while infants and children need around 1.2 mcg. Pregnant and lactating women require additional intake.
“The RDA (recommended dietary allowance) requirements can be met by opting for vitamin B12-rich foods, particularly from animal sources like red meat, fish, poultry, and eggs. Vegetarians can opt for foods like milk, yogurt, cheese, fortified cereals or milk and milk products. Including foods rich in folic acid like green leafy, beans, peanut, broccoli, peas, lentils, along with B12 rich foods may help prevent the risk of developing anaemia,” Puri explained.
If unable to meet needs through food sources, Vitamin B12 supplements may prove beneficial. Maintaining a healthy balanced diet along with regular checkups can also help in identifying vitamin B12 deficiency, reducing the risk of complications, he added.
2025-01-21T07:22:48Z